Yeast and bacteria are the most common organisms encountered in cutaneous cytologic examinations, and Malassezia pachydermatis is the most common yeast found in skin samples from dogs and cats. However, other Malassezia and Candida species can also be found in the skin, ears, and oral cavity. Malassezia species usually appear as classic budding yeast (footprint shape), as seen in this sample obtained by direct impression from this dog’s ventral cervical intertriginous area that has associated alopecia and lichenification (modified Wright’s stain, 100X). In my experience, average yeast counts as low as 1 or 2 organisms per oil immersion field can be clinically relevant in samples from inflamed skin or ears. In this slide, more than 50 organisms are visible.